Previously unrecognized immune response could enhance defense against cancer
In a paradigm breaking study, Pavan Reddy, M.D., director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine, and his team, with collaborators from the University of Michigan Rogel Cancer Center, discovered a novel way the immune system, specifically T-cells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications for the field of cancer immunology and bone marrow transplantation. The study appeared in Nature Immunology.
“Our work, if further validated, will have implications for T cell-mediated immune responses beyond cancer and transplant immunology,” Dr. Reddy said. “This may allow for the development of novel strategies that target MHC class I and CD4+ T cells to leverage the beneficial side of immunity or mitigate unwanted immune responses.”
This work was supported by grants from the National Institutes of Health and by the Cancer Prevention and Research Institute of Texas (CPRIT). Because CPRIT requires institutions to provide matching funds, your philanthropic support helped make this exciting breakthrough happen.
Read the full press release here.
